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SPRUCE BIOSCIENCES, INC.

For the period ended Sep 30, 2025. Filed Nov 10, 2025.

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A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2025 · Filed Nov 10, 2025

SPRB$46.55+9.0%Stored close · as of Nov 6, 2026

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Other Information

Termination of Loan Agreement

On November 4, 2025, we gave notice, effective as of November 7, 2025, of our termination of the Loan Agreement with SVB. The Loan Agreement, as amended, provided for a term loan facility in a principal amount of $5.0 million and was scheduled to mature on January 1, 2026. On November 3, 2025, we voluntarily prepaid in full the outstanding principal balance of the Term Loan, which was $0.4 million, and all accrued and unpaid interest and fees under the Term Loan including the Supplemental Final Payment of $0.3 million.

Insider Trading Arrangements

During our last fiscal quarter, no director or officer (as defined in Rule 16a-1(f) under the Exchange Act)adopted orterminated a “Rule 10b5-1 trading arrangement” or “non-Rule 10b5-1 trading arrangement,” as each term is defined in Item 408(a) of Regulation S-K.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.