Immunome Inc.
For the period ended Sep 30, 2025. Filed Nov 6, 2025.
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A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.
Sep 30, 2025 · Filed Nov 6, 2025
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11. Segment information
The Company hasone operating and reportable segment related to the development of targeted oncology therapies. The segment derives its current revenues from research and development collaborations.
The CODM assesses performance for the segment based on net loss, which is reported on the condensed consolidated statements of operations and comprehensive loss as net loss. The measure of segment assets is reported on the condensed consolidated balance sheets as total assets. When evaluating the Company’s financial performance, the CODM regularly reviews total revenues, total expenses and research and development expenses by program.
The table below is a summary of the segment net loss, including significant segment expense categories (in thousands):
| Three Months Ended September 30, | Nine Months Ended September 30, | |||
|---|---|---|---|---|
| 2025 | 2024 | 2025 | 2024 | |
| Collaboration revenue | $— | $2,910 | $6,941 | $6,303 |
| Less: | ||||
| In-process research and development | — | (6,706) | — | (124,972) |
| Direct research and development expenses(1) | ||||
| Varegacestat | (12,495) | (9,621) | (39,615) | (14,397) |
| IM-1021 | (2,874) | (4,456) | (7,669) | (14,865) |
| IM-3050 | (2,104) | (4,080) | (4,149) | (9,234) |
| Other product candidates | (17,623) | (10,917) | (35,672) | (25,418) |
| Indirect research and development(2) | (14,097) | (8,126) | (39,411) | (17,738) |
| General and administrative(3) | (10,945) | (9,526) | (31,677) | (22,509) |
| Total operating expenses | (60,138) | (53,432) | (158,193) | (229,133) |
| Loss from operations | (60,138) | (50,522) | (151,252) | (222,830) |
| Interest income | 2,681 | 3,422 | 8,758 | 10,116 |
| Net loss | $(57,457) | $(47,100) | $(142,494) | $(212,714) |
(1)
Direct research and development expenses include external costs, such as costs related to laboratory materials and services, manufacturing, outsourced research, product development, and clinical trial costs, including fees paid to investigators, consultants, central laboratories and CROs to specific product candidates.
(2)
Indirect research and development expenses include personnel salary, benefit and share-based compensation costs, depreciation and amortization and certain overhead expenses.
(3)
General and administrative expenses include personnel salary, benefit and share-based compensation costs, legal fees, professional fees for accounting, auditing, tax and consulting services, insurance costs, travel, depreciation and amortization, and certain overhead expenses.
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