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Karyopharm Therapeutics Inc.

For the period ended Sep 30, 2025. Filed Nov 3, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2025 · Filed Nov 3, 2025

KPTI$0.02-56.5%Stored close · as of Nov 10, 2026

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Condensed Consolidated Statements of Operations

(in thousands, except per share amounts)

For the Three Months Ended September 30,For the Nine Months Ended September 30,
2025202420252024
Revenues:
Product revenue, net$32,032$29,516$82,767$83,554
License and other revenue12,0129,26729,22131,141
Total revenue44,04438,783111,988114,695
Operating expenses:
Cost of sales2,1131,3004,4654,676
Research and development30,54436,13497,950109,930
Selling, general and administrative26,60727,63282,43688,251
Total operating expenses59,26465,066184,851202,857
Loss from operations(15,220)(26,283)(72,863)(88,162)
Other income (expense):
Interest income5531,8322,1665,918
Interest expense(11,008)(11,385)(33,230)(26,218)
Gain on extinguishment of debt———44,702
Other (expense) income, net(7,418)3,79210,19618,284
Total other (expense) income, net(17,873)(5,761)(20,868)42,686
Loss before income taxes(33,093)(32,044)(93,731)(45,476)
Income tax provision(34)(28)(110)(166)
Net loss$(33,127)$(32,072)$(93,841)$(45,642)
Basic net loss per share$(3.82)$(3.85)$(10.93)$(5.68)
Diluted net loss per share (Note 7)$(3.82)$(3.85)$(10.93)$(10.40)
Weighted-average number of common shares outstanding used to compute basic net loss per share8,6698,3368,5878,036
Weighted-average number of common shares outstanding used to compute diluted net loss per share8,6698,3368,5878,442
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.