| Exhibit No. | Description |
| 3.1 | Certificate of Incorporation of Anika Therapeutics, Inc. (incorporated by reference to Exhibit 3.1 to the Current Report on Form 8-K (File No. 001-14027) filed by the Registrant on June 6, 2018) |
| 3.2 | Bylaws of Anika Therapeutics, Inc., effective as of June 6, 2018 (incorporated by reference to Exhibit 3.2 to the Current Report on Form 8-K (File No. 001-14027) filed by the Registrant on June 6, 2018) |
| 10.2† | Anika Therapeutics, Inc. 2017 Omnibus Incentive Plan (as amended effective June 20, 2025) (incorporated by reference to Exhibit 10.1 to the Current Report on Form 8-K filed on June 24, 2025) |
| (31) | Rule 13a-14(a)/15d-14(a) Certifications |
| *31.1 | Certification of Dr. Cheryl R. Blanchard, pursuant to Rules 13a-15(e) and 15d-15(e), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. |
| *31.2 | Certification of Stephen Griffin, pursuant to Rules 13a-15(e) and 15d-15(e), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. |
| (32) | Section 1350 Certifications |
| **32.1 | Certification of Dr. Cheryl R. Blanchard, and Stephen Griffin, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. |
| (101) | XBRL |
| *101 | The following materials from Anika Therapeutics, Inc.’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 as filed with the SEC on July 30, 2025, formatted in Inline XBRL (eXtensible Business Reporting Language), as follows: |
| i. | Condensed Consolidated Balance Sheets as of June 30, 2025 (unaudited) and December 31, 2024 (unaudited) |
| ii. | Condensed Consolidated Statements of Operations and Comprehensive Income for the Three and Six Months Ended June 30, 2025 and June 30, 2024 (unaudited) |
| iii. | Condensed Consolidated Statements of Stockholders’ Equity for the Six Months Ended June 30, 2025 and June 30, 2024 (unaudited) |
| iv. | Condensed Consolidated Statements of Cash Flows for the Six Months Ended June 30, 2025 and June 30, 2024 (unaudited) |
| v. | Notes to Condensed Consolidated Financial Statements (unaudited) |
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101) |
† Management contract or compensatory plan or agreement.
