ILLUMINA, INC.

During the quarterly period ended September 27, 2026, the following directors or officers adopted, modified, or terminated 10b5-1 plans:

•On August 25, 2026, Kevin Pegels, our Chief of Global Operations, entered into a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on September 1, 2027 and provides for the sale of up to 3,900 shares.

•On September 1, 2026, Patricia Leckman, our Chief People Officer, entered into a new arrangement intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). The arrangement terminates on September 1, 2027 and provides for the sale of up to 5,116 shares.

•On August 14, 2026, Scott Davies, our former Chief Legal Officer, terminated a trading arrangement he had previously adopted with respect to the sale of securities of the Company’s common stock (a “Rule 10b5-1 Trading Arrangement”) in connection with his departure from the Company. Mr. Davies’ Rule 10b5-1 Trading Arrangement was adopted on November 21, 2025, had a termination date of December 28, 2026, and provided for the sale of up to 4,251 shares of common stock pursuant to the terms of the plan.

Other than as disclosed above, during the quarterly period ended September 27, 2026, none of the Company’s directors or officers adopted, modified, or terminated any “Rule 10b5-1 trading arrangement” or any “non-Rule 10b5-1 trading arrangement,” in each case as such term is defined in Item 408 of Regulation S-K.