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ILLUMINA, INC.

For the period ended Dec 28, 2025. Filed Feb 12, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 12, 2026

ILMN$214.91-2.7%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Index to Exhibits

Incorporated by Reference
Exhibit · Filing · Filed
Number · Exhibit Description · Form · File Number · Exhibit · Date · Herewith
2.1*Stock Purchase Agreement, dated June 22, 2025, between Illumina, Inc. and Standard BioTools Inc.8-K001-354062.16/23/2025
3.1Amended and Restated Certificate of Incorporation10-Q001-354063.18/11/2022
3.2Amended and Restated Bylaws10-Q001-354063.18/7/2024
4.1Specimen Common Stock CertificateS-1/A333-339224.17/3/2000
4.3Description of Illumina, Inc.’s securities registered pursuant to Section 12 of the Exchange Act of 193410-K001-354064.52/17/2021
4.4Indenture, dated as of March 12, 2021, by and between Illumina, Inc. and U.S. Bank Trust Company, National Association (as successor in interest to U.S. Bank National Association), as trustee (incorporated by reference to Exhibit 4.6 to Illumina’s Registration Statement on Form S-3 (File No. 333-254195)S-3333-541954.63/12/2021
4.5Form of Officer's Certificate setting forth the terms and forms of the 2023 Notes and 2031 Notes8-K001-354064.23/22/2021
4.6Contingent Value Rights Agreement by and among Illumina, Inc., Computershare Trust Company, N.A., as Trustee and Shareholder Representative Services LLC dated as of August 18, 20218-K001-354064.18/18/2021
4.7Form of Officer’s Certificate setting forth the terms and forms of the 2025 Notes and 2027 Notes8-K001-354064.212/13/2022
4.8Officer’s Certificate, dated November 25, 2025, setting forth the terms and form of the Notes8-K001-354064.211/25/2025
+10.1Form of Indemnification Agreement between Illumina and each of its directors and executive officers10-Q000-3036110.557/25/2008
+10.2Form of Change in Control Severance Agreement between Illumina and each of its executive officers10-K000-3036110.342/26/2009
+10.32000 Employee Stock Purchase Plan, as amended and restated through May 2, 202310-Q001-3540610.18/10/2023
+10.4New Hire Stock and Incentive Plan, as amended and restated through October 28, 200910-K000-3036110.72/26/2010
10.5License Agreement, effective as of May 6, 1998, between Tufts University and Illumina10-Q000-3036110.55/3/2007
+10.6The Solexa Unapproved Company Share Option Plan8-K000-3036199.311/26/2007
+10.7The Solexa Share Option Plan for Consultants8-K000-3036199.411/26/2007
+10.8Solexa Limited Enterprise Management Incentive Plan8-K000-3036199.511/26/2007
+10.9Amended and Restated Solexa 2005 Equity Incentive Plan10-K000-3036110.252/26/2009
+10.10Amended and Restated Solexa 1992 Stock Option Plan10-K000-3036110.262/26/2009
+10.11Amended and Restated 2015 Stock and Incentive Plan8-K001-3540610.12/7/2023
+10.12Form of Restricted Stock Unit Agreement for Employees Under Amended and Restated 2015 Stock and Incentive Plan8-K001-3540610.42/7/2023
+10.13Form of Performance Stock Unit Agreement (Relative TSR) for Employees Under Amended and Restated 2015 Stock and Incentive Plan8-K001-3540610.22/7/2023
+10.14Form of Performance Stock Unit Agreement (Adjusted EPS) for Employees Under Amended and Restated 2015 Stock and Incentive Plan8-K001-3540610.32/7/2023
+10.15Form of Option Agreement for Employees Under 2015 Stock and Incentive Plan10-K001-3540610.152/17/2023
10.16Amended and Restated Lease Agreement, dated March 27, 2012, between ARE-SD Region No. 32, LLC and Illumina10-Q001-3540610.15/3/2012
10.17First Amendment to Amended and Restated Lease Agreement, dated March 27, 2012, between ARE-SD Region No. 32, LLC and Illumina10-K001-3540610.232/18/2015
10.18Second Amendment to Amended and Restated Lease Agreement, dated March 27, 2012, between ARE-SD Region No. 32, LLC and Illumina10-K001-3540610.242/18/2015
10.19Amended and Restated Second Amendment to Amended and Restated Lease Agreement, dated March 27, 2012, between ARE-SD Region No. 32, LLC and Illumina10-K001-3540610.182/13/2018
+10.20Deferred Compensation Plan, effective December 1, 200714D-9005-6045799(e)(6)2/7/2012
10.21Lease between BMR-Lincoln Centre LP and Illumina, dated December 30, 201410-K001-3540610.262/18/2015
10.22Pooled Patents Agreement between Illumina and Sequenom, Inc., dated December 2, 2014 (with certain confidential portions omitted)10-K001-3540610.272/18/2015
10.23First Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of April 21, 201610-K001-3540610.222/13/2018
10.24Second Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of April 17, 201710-K001-3540610.232/13/2018
10.25Third Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of August 28, 2017 (with certain confidential portions omitted)10-K001-3540610.242/13/2018
10.26Fourth Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of March 15, 201810-K001-3540610.252/11/2020
10.27Fifth Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of April 12, 2019 (with certain confidential portions omitted)10-K001-3540610.252/11/2020
10.28Sixth Amendment to Pooled Patents Agreement between Illumina and Sequenom, Inc., effective as of May 8, 2020 (with certain confidential portions omitted)10-Q001-3540610.110/30/2020
10.29Agreement for Lease between Granta Park Park Jco 1 Limited and Illumina, dated June 25, 201510-Q001-3540610.17/31/2015
10.30Third Amendment to Lease between ARE-SD Region No. 32, LLC and Illumina, dated September 2, 201510-K001-3540610.293/2/2016
10.31First Amendment to Lease between BMR-Lincoln Center LP and Illumina, dated February 23, 201610-K001-3540610.303/2/2016
10.32Fourth Amendment to Lease between ARE-SD Region No. 32, LLC and Illumina, dated April 14, 201610-K001-3540610.282/14/2017
10.33Second Amendment to Lease between BMR-Lincoln Center LP and Illumina dated August 15, 201610-K001-3540610.292/14/2017
10.34Deed of Variation to the Agreement for Lease between Granta Park Jco 1 Limited and Illumina dated October 24, 201610-K001-3540610.302/14/2017
10.35Third Amendment to Lease between BMR-Lincoln Center LP and Illumina dated January 18, 201810-Q001-3540610.104/25/2018
+10.36Form of Insurance Matters Agreement10-Q001-3540610.111/5/2021
10.37Credit Agreement, dated as of January 4, 2023, among the Company, as the borrower, the lenders from time to time party thereto, Bank of America, N.A., as administrative agent, an issuing bank and the swingline lender, and the other issuing banks from time to time party thereto8-K001-3540610.11/4/2023
+10.38Separation Agreement and Release of All Claims by and between Illumina, Inc. and Kathryne Reeves, dates of March 19, 202410-Q001-3540610.15/3/2024
10.39Tax Matters Agreement, dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.8-K001-3540610.16/24/2024
10.40Employee Matters Agreement, dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.8-K001-3540610.26/24/2024
10.41Stockholder and Registration Rights Agreement, Dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.8-K001-3540610.36/24/2024
10.42Fourth Amendment to the Amended and Restated Supply and Commercialization Agreement, dated June 21, 2024, by and between Illumina, Inc. and GRAIL, LLC*8-K001-3540610.46/24/2024
10.43364-Day Delayed Draw Credit Agreement, dated as of June 17, 2024, among the Company, as the borrower, the lenders from time to time party thereto and JPMorgan Chase Bank, N.A., as administrative agent Fourth Amendment to the Amended and Restated Supply and Commercialization Agreement, dated June 21, 2024, by and between Illumina, Inc. and GRAIL, LLC*8-K001-3540610.16/17/2024
+10.44Retention Agreement by and between Joydeep Goswami and Illumina, Inc. dated as of April 8, 202410-Q001-3540610.68/7/2024
+10.45Separation Agreement and General Release of All Claims by and between Joydeep Goswami and Illumina, Inc. dated as of July 2, 202410-Q001-3540610.78/7/2024
10.46Underwriting Agreement, dated September 4, 2024, between the Company and J.P. Morgan Securities LLC and Goldman Sachs & Co. LLC, as representatives of the several underwriters named therein8-K001-354061.19/9/2024
10.47Officer’s Certificate, dated September 9, 2024, setting forth the terms and form of the Notes8-K001-354064.29/9/2024
+10.48Advisory Agreement between Illumina, Inc. and Charles Dadswell, dated October 3, 20248-K001-3540610.110/3/2024
+10.49Separation Agreement between Illumina, Inc. and Charles Dadswell, dated October 3, 20248-K001-3540610.210/3/2024
10.50Underwriting Agreement, dated November 10, 2025 between Illumina and Goldman Sachs & Co. LLC and BofA Securities, Inc., as representatives of the several underwriters named therein8-K001-354061.111/12/2025
+19.1Insider Trading Policy, Adopted May 6, 2025X
21.1Subsidiaries of IlluminaX
23.1Consent of Independent Registered Public Accounting FirmX
24.1Power of Attorney (included on the signature page)X
31.1Certification of Jacob Thaysen pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
31.2Certification of Ankur Dhingra pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
32.1Certification of Jacob Thaysen pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
32.2 · Certification of Ankur Dhingra pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 · X
+97.1Compensation Recovery/Clawback Policy - Adopted May 2, 202310-K001-3540697.12/16/2024
101.INSXBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL documentX
101.SCHXBRL Taxonomy Extension SchemaX
101.CALXBRL Taxonomy Extension Calculation LinkbaseX
101.LABXBRL Taxonomy Extension Label LinkbaseX
101.PREXBRL Taxonomy Extension Presentation LinkbaseX
101.DEFXBRL Taxonomy Extension Definition LinkbaseX
104Cover Page Interactive Data File - formatted in Inline XBRL and included as Exhibit 101X
+Management contract or corporate plan or arrangement
*Portions of this exhibit omitted pursuant to Item 601(a)(5), Item 601(b)(2) or Item 601(b)(10) of Regulation S-K, as applicable. The Company agrees to furnish a supplemental and unredacted copy of any agreement or omitted schedule to the Securities and Exchange Commission upon its request.

Supplemental Information

No Annual Report to stockholders or proxy materials has been furnished to stockholders as of the date of this report. The Annual Report to stockholders and proxy material will be furnished to our stockholders after the filing of this Annual Report on Form 10-K and we will furnish such material to the SEC at that time.

ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.