ALUMIS INC.

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant ☒

Filed by a party other than the Registrant ☐

Check the appropriate box:

☐

Preliminary Proxy Statement

​

☐

Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

​

☒

Definitive Proxy Statement

​

☐

Definitive Additional Materials

​

☐

Soliciting Material under § 240.14a-12

​

Alumis Inc.

​

(Name of Registrant as Specified in Its Charter)

​

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)​

Payment of Filing Fee (Check all boxes that apply):

☒

No fee required

​

☐

Fee paid previously with preliminary materials

​

☐

Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11

​

ALUMIS INC.

280 East Grand Avenue

South San Francisco, California 94080

NOTICE OF THE 2026 ANNUAL MEETING OF STOCKHOLDERS

To Be Held on June 30, 2026

Dear Alumis Inc. Stockholders:

You are cordially invited to attend the 2026 Annual Meeting of Stockholders (the “Annual Meeting”) of Alumis Inc. (“we” or “us,” or the “Company”), which will be held on Tuesday, June 30, 2026 at 9:00 a.m. Pacific Time. The Annual Meeting will be a virtual meeting conducted exclusively online via live audio webcast.

The Annual Meeting will be held for the following purposes, as more fully described in the accompanying proxy statement (“Proxy Statement”):

1. To elect the three Class II director nominees named in the Proxy Statement to serve until the 2029 Annual Meeting of Stockholders;

2. To ratify the appointment of PricewaterhouseCoopers LLP as the Company’s independent auditor for our fiscal year ending December 31, 2026; and

3. To conduct any other business that may properly come before the Annual Meeting or any postponement or adjournment thereof.

The Annual Meeting can be attended by visitingwww.virtualshareholdermeeting.com/ALMS2026 and entering your 16-digit Control Number included in your Notice of Internet Availability of Proxy Materials, proxy card or voting instruction form sent to you. You may log in to the Annual Meeting beginning at 8:45 a.m. Pacific Time, on Tuesday, June 30, 2026. Please refer to the additional instructions for attending the virtual Annual Meeting and recommendations provided in the accompanying Proxy Statement.

The record date for the Annual Meeting is May 5, 2026. Only stockholders of record at the close of business on that date are entitled to notice of, and may vote at, the Annual Meeting, or any adjournment or postponement thereof.

By Order of the Board of Directors

/s/ Sanam Pangali

​

Sanam Pangali

Chief Legal Officer and Corporate Secretary

South San Francisco, California

May 18, 2026