Protagonist Therapeutics, Inc
For the period ended Sep 30, 2025. Filed Nov 6, 2025.
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A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.
Sep 30, 2025 · Filed Nov 6, 2025
PTGX$136.26+0.3%Stored close · as of Nov 10, 2026
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Condensed Consolidated Statements of Cash Flows
(In thousands)
| | | | | | | |
|---|---|---|---|---|---|---|
| · · Nine Months Ended | ||||||
| · · September 30, | ||||||
| · 2025 · 2024 | ||||||
| Cash Flows from Operating Activities · · · | ||||||
| Net (loss) income | | $(85,765) | | $143,514 | ||
| Adjustments to reconcile net (loss) income to net cash provided by operating activities: | | | | | | |
| Stock-based compensation | | | 35,273 | | | 28,461 |
| Non-cash lease expense | | | 1,243 | | | 1,651 |
| Depreciation | | | 904 | | | 708 |
| Accretion of discount on marketable securities | | | (5,887) | | | (6,115) |
| Net realized loss on sale of marketable securities | | | 4 | | | — |
| Changes in operating assets and liabilities: | | | | | | |
| Receivable from collaboration partner | | | 164,417 | | | 10,000 |
| Prepaid expenses and other assets | | | (1,995) | | | (4,088) |
| Accounts payable | | | 4,030 | | | 2,272 |
| Accrued expenses and other payables | | | (833) | | | 1,061 |
| Payable to collaboration partner | | | — | | | (3) |
| Income taxes payable | | | (2,689) | | | 1,049 |
| Deferred revenue | | | (13,579) | | | 36,205 |
| Operating lease liability | | | (477) | | | (1,385) |
| Net cash provided by operating activities | | | 94,646 | | | 213,330 |
| Cash Flows from Investing Activities | | | | | | |
| Purchase of marketable securities | | | (442,311) | | | (507,293) |
| Proceeds from maturities of marketable securities | | | 338,607 | | | 217,580 |
| Proceeds from sale of marketable securities | | | 7,003 | | | — |
| Purchases of property and equipment | | | (1,446) | | | (1,045) |
| Net cash used in investing activities | | | (98,147) | | | (290,758) |
| Cash Flows from Financing Activities | | | | | | |
| Proceeds from issuance of common stock upon exercise of stock options and purchases under employee stock purchase plan | | | 20,506 | | | 22,422 |
| Tax withholding payments related to net settlement of restricted stock units | | | (479) | | | (600) |
| Net cash provided by financing activities | | | 20,027 | | | 21,822 |
| Net increase (decrease) in cash, cash equivalents and restricted cash | | | 16,526 | | | (55,606) |
| Cash, cash equivalents and restricted cash, beginning of period | | 97,474 | | 186,952 | ||
| Cash, cash equivalents and restricted cash, end of period | | $114,000 | | $131,346 | ||
| Supplemental Disclosure of Non-Cash Financing and Investing Information: | | | | | | |
| Leasehold improvements obtained under tenant improvement allowance | | $360 | | $613 | ||
| Purchases of property and equipment in accounts payable and accrued liabilities | | $8 | | $325 | ||
| Right-of-use asset obtained in exchange for lease obligation | | $— | | $10,511 | ||
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