Septerna, Inc.

For the period ended Jun 30, 2025. Filed Aug 11, 2025.

About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2025 · Filed Aug 11, 2025

SEPN$52.34+3.2%Stored close · as of Nov 10, 2026

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Condensed Statements of Operations and Comprehensive Loss

(In thousands, except for share and per share data)

	Three Months Ended June 30,		Six Months Ended June 30,
	2025	2024	2025	2024
Revenue	$119	$370	$338	$687
Operating expenses:
Research and development	22,188	15,035	41,459	28,188
General and administrative	6,909	3,400	13,767	6,054
Total operating expenses	29,097	18,435	55,226	34,242
Loss from operations	(28,978)	(18,065)	(54,888)	(33,555)
Other income, net:
Interest income	4,165	1,530	8,627	2,809
Other expense, net	(25)	(15)	(53)	(63)
Total other income, net	4,140	1,515	8,574	2,746
Loss before benefit for income taxes	(24,838)	(16,550)	(46,314)	(30,809)
Benefit for income taxes	—	109	—	202
Net loss attributable to common stockholders	$(24,838)	$(16,441)	$(46,314)	$(30,607)
Net loss per share attributable to common stockholders, basic and diluted	$(0.56)	$(7.03)	$(1.05)	$(13.40)
Weighted-average shares outstanding, basic and diluted	44,165,168	2,337,585	44,051,918	2,284,414
Comprehensive loss:
Net loss	$(24,838)	$(16,441)	$(46,314)	$(30,607)
Net unrealized gain (loss) on marketable securities	(22)	(1)	120	(8)
Total other comprehensive income (loss)	(22)	(1)	120	(8)
Comprehensive loss	$(24,860)	$(16,442)	$(46,194)	$(30,615)

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