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Karyopharm Therapeutics Inc.

For the period ended Jun 30, 2025. Filed Aug 11, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2025 · Filed Aug 11, 2025

KPTI$0.04-27.1%Stored close · as of Nov 9, 2026

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Condensed Consolidated Statements of Operations

(in thousands, except per share amounts)

For the Three Months Ended June 30,For the Six Months Ended June 30,
2025202420252024
Revenues:
Product revenue, net$29,681$28,032$50,735$54,038
License and other revenue8,24814,75417,20921,874
Total revenue37,92942,78667,94475,912
Operating expenses:
Cost of sales1,0511,4652,3523,376
Research and development32,78838,37167,40673,796
Selling, general and administrative28,47731,07055,82960,619
Total operating expenses62,31670,906125,587137,791
Loss from operations(24,387)(28,120)(57,643)(61,879)
Other income (expense):
Interest income6131,9301,6134,086
Interest expense(11,228)(8,949)(22,222)(14,833)
Gain on extinguishment of debt—44,702—44,702
Other (expense) income, net(2,210)14,29617,61414,492
Total other income (expense), net(12,825)51,979(2,995)48,447
(Loss) income before income taxes(37,212)23,859(60,638)(13,432)
Income tax provision(40)(67)(76)(138)
Net (loss) income$(37,252)$23,792$(60,714)$(13,570)
Basic net (loss) income per share (Note 7)$(4.32)$2.26$(7.11)$(1.72)
Diluted net loss per share (Note 7)$(4.32)$(2.97)$(7.11)$(7.16)
Weighted-average number of common shares outstanding used to compute basic net (loss) income per share8,6208,0698,5457,884
Weighted-average number of common shares outstanding used to compute diluted net loss per share8,62010,2958,5458,472
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.