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Wave Life Sciences Ltd

For the period ended Dec 31, 2024. Filed Mar 4, 2025.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2024 · Filed Mar 4, 2025

WVE$3.41-2.0%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits and Financial Statement Schedules

(a)

The following documents are filed as part of this report:

  1. Financial Statements

See Index to Consolidated Financial Statements on page 108 of this Annual Report on Form 10-K.

  1. Financial Statement Schedules

All schedules are omitted because they are not applicable, or the required information is shown in the financial statements or notes thereto.

  1. Exhibits

The following is a list of exhibits filed as part of this Annual Report on Form 10-K.

ExhibitNumberExhibit DescriptionFiledwiththisReportIncorporated byReference hereinfrom Form orScheduleFiling DateSECFile/Reg.Number
3.1Constitution (formerly known as Memorandum of Association and Articles of Association)Amendment No. 5to Form S-1(Exhibit 3.2)11/10/2015333-207379
4.1Form of Specimen Ordinary Share CertificateAmendment No. 3to Form S-1(Exhibit 4.1)11/06/2015333-207379
4.2Description of Securities of the Registrant and Comparison of Shareholder RightsX
4.3.1Form of Pre-Funded Warrant (2022)Form 8-K(Exhibit 4.1)06/14/2022001-37627
4.3.2Form of Pre-Funded Warrant (2024)Form 8-K(Exhibit 4.1)9/26/2024001-37627
4.4Share Purchase Agreement by and between the Registrant and C.P. Pharmaceuticals International C.V., dated as of May 5, 2016Form 10-Q(Exhibit 10.2)08/15/2016001-37627
Lease Agreements
10.1.1Lease Agreement by and between Wave Life Sciences USA, Inc., the Registrant, and King 733 Concord LLC, dated as of April 6, 2015Form S-1(Exhibit 10.7)10/09/2015333-207379
10.1.2First Amendment (to Lease) by and between Wave Life Sciences USA, Inc. and CPI/King 733 Concord Owner, LLC, dated as of December 9, 2020Form 10-K(Exhibit 10.5.2)03/04/2021001-37627
10.1.3Second Amendment (to Lease) by and between Wave Life Sciences USA, Inc. and CPI/King 733 Concord Owner, LLC, dated as of August 8, 2022Form 10-Q(Exhibit 10.1)08/11/2022001-37627
10.2.1Lease Agreement by and between Wave Life Sciences USA, Inc. and King 115 Hartwell LLC, dated as of September 26, 2016Form 8-K(Exhibit 10.1)01/06/2017001-37627
10.2.2First Amendment (to Lease) by and between Wave Life Sciences USA, Inc. and King 115 Hartwell LLC, dated as of December 31, 2016Form 8-K(Exhibit 10.1)01/06/2017001-37627
Collaboration and License Agreements
10.3††Collaboration and License Agreement by and between Wave Life Sciences USA, Inc., Wave Life Sciences UK Limited and GlaxoSmithKline Intellectual Property (No. 3), dated as of December 13, 2022Form 10-K(Exhibit 10.3)03/23/2023001-37627
10.4Share Purchase Agreement by and between Glaxo Group Limited and the Registrant, dated as of December 13, 2022Form 10-K(Exhibit 10.4)03/23/2023001-37627
10.5Investor Agreement by and between Glaxo Group Limited and the Registrant, dated as of January 26, 2023Form 10-K(Exhibit 10.5)03/23/2023001-37627
Agreements with Executive Officers and Directors
10.6+Form of Deed of Indemnity by and between the Registrant and each of its directors and certain of its officersForm S-1(Exhibit 10.11)10/09/2015333-207379
10.7+Employment Agreement, as amended and restated, between the Registrant and Paul B. Bolno, dated as of May 8, 2020Form 10-Q(Exhibit 10.1)08/10/2020333-207379
10.8+Employment Agreement, as amended and restated, between the Registrant and Chandra Vargeese, dated as of May 8, 2020Form 10-Q(Exhibit 10.2)08/10/2020333-207379
10.9+Employment Agreement between the Registrant and Christopher Francis, Ph.D., dated as of November 8, 2022Form 10-K(Exhibit 10.12)03/23/2023001-37627
10.10+Employment Agreement, as amended and restated, between the Registrant and Kyle Moran, dated as of January 1, 2021Form 10-K(Exhibit 10.15)03/04/2021001-37627
10.11+Non-Employee Director Compensation Policy, as amended, effective as of August 6, 2024Form 10-Q(Exhibit 10.2+)11/12/2024001-37627
10.12+Consulting Agreement by and between Ontorii, Inc. (now Wave Life Sciences USA, Inc.) and Gregory Verdine, dated as of April 1, 2012Form S-1(Exhibit 10.16)10/09/2015333-207379
Equity and Other Compensation Plans
10.13+Wave Life Sciences Ltd. 2014 Equity Incentive Plan, as amended (the “2014 Equity Plan”)Form 10-Q(Exhibit 10.1)11/09/2017001-37627
10.14+Wave Life Sciences Ltd. 2021 Equity Plan, as amended, (the “2021 Equity Plan”) effective August 6, 2024Form 8-K(Exhibit 10.1)08/12/2024001-37627
10.15+Wave Life Sciences Ltd. 2019 Employee Share Purchase Plan, as amended, effective as of August 1, 2023Form 8-K(Exhibit 10.2)08/07/2023001-37627
10.16.1+Form of Non-qualified Share Option Agreement under the 2014 Equity Plan, effective as of September 20, 2016Form 10-Q(Exhibit 10.2)11/09/2017001-37627
10.16.2+Form of Non-qualified Share Option Agreement under the 2014 Equity Plan, effective as of January 1, 2018Form 10-K(Exhibit 10.23.3)03/01/2019001-37627
10.16.3+Form of Non-qualified Share Option Agreement under the 2021 Equity Plan, effective as August 10, 2021Form 10-K(Exhibit 10.3)11/10/2021001-37627
10.17.1+Form of Incentive Share Option Agreement under the 2014 Equity Plan, effective as of December 2014Form S-8(Exhibit 10.1)12/17/2015333-208598
10.17.2+Form of Incentive Share Option Agreement under the 2014 Equity Plan, effective as of September 20, 2016Form 10-Q(Exhibit 10.3)11/09/2017001-37627
10.18.1+Form of Restricted Share Unit Agreement under the 2014 Equity Plan, effective as of June 16, 2016Form 10-Q(Exhibit 10.4)11/09/2017001-37627
10.18.2+Form of Restricted Share Unit Agreement under the 2014 Equity Plan, effective as of January 1, 2018Form 10-K(Exhibit 10.25.2)03/01/2019001-37627
10.18.3+Form of Restricted Share Unit Agreement under the 2014 Equity Incentive Plan, effective as of January 1, 2019Form 10-Q(Exhibit 10.1)05/10/2019001-37627
10.18.4+Form of Restricted Share Unit Agreement under the 2021 Equity Plan, effective as of August 10, 2021Form 10-Q(Exhibit 10.4)11/10/2021001-37627
10.18.5+Form of Amended and Restated 2019 Performance-Based Restricted Share Unit Agreement under the 2014 Equity Incentive Plan, effective as of March 17, 2021Form 10-Q(Exhibit 10.2)05/13/2021001-37627
10.18.6+Form of 2021 Performance-Based Restricted Share Unit Agreement under the 2014 Equity Incentive Plan, effective as of March 17, 2021Form 10-Q(Exhibit 10.3)05/13/2021001-37627
10.19.1+Form of Non-qualified Share Option Agreement for UK Participants under the 2014 Equity Plan, effective as of June 21, 2017Form 10-Q(Exhibit 10.5)11/09/2017001-37627
10.19.2+Form of Non-qualified Share Option Agreement for UK Participants under the 2014 Equity Plan, effective as of January 1, 2018Form 10-K(Exhibit 10.26.2)03/01/2019001-37627
10.19.3+Form of Non-qualified Share Option Agreement for UK Participants under the 2021 Equity Plan, effective as of August 10, 2021Form 10-Q(Exhibit 10.5)11/10/2021001-37627
10.19.4+Form of Restricted Share Unit Agreement for UK Participants under the 2021 Equity Plan, effective as of August 10, 2021Form 10-Q(Exhibit 10.6)11/10/2021001-37627
10.20.1+Form of Inducement Non-qualified Share Option Agreement, effective May 2024Form 10-Q(Exhibit 10.1)08/08/2024001-37627
10.20.2+Form of Inducement Restricted Share Unit Agreement, effective May 2024Form 10-Q(Exhibit 10.2)08/08/2024001-37627
10.21.1Open Market Sale Agreement, dated as of May 10, 2019, by and between the Registrant and Jefferies LLCForm S-3ASR(Exhibit 1.2)05/10/2019333-231382
10.21.2Amendment No. 1 to Open Market Sale Agreement, dated as of March 2, 2020, by and between the Registrant and Jefferies LLCPOSASR(Exhibit 1.3)03/02/2020333-231382
10.21.3Amendment No. 2, dated March 3, 2022, to the Open Market Sale Agreement, dated as of May 10, 2019, by and between Wave Life Sciences Ltd. and Jefferies LLCForm 8-K(Exhibit 10.1)03/03/2022001-37627
10.21.4Amendment No. 3, dated November 12, 2024, to the Open Market Sale Agreement, dated as of May 10, 2019, by and between Wave Life Sciences Ltd. and Jefferies LLCForm 10-Q(Exhibit 10.1)11/12/2024001-37627
19.1Insider Trading PolicyX
23.1Consent of Independent Registered Public Accounting FirmX
31.1Certifications of Principal Executive Officer pursuant to Rule 13a-14(a)X
31.2Certifications of Principal Financial Officer pursuant to Rule 13a-14(a)X
32*Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, by Principal Executive Officer and Principal Financial OfficerX
97.1Clawback Policy, effective as of October 2, 2023Form 10-K(Exhibit 97.1)03/06/2024001-37627
101.INSXBRL Instance Document – The Instance Document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL documentX
101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase DocumentsX
104The cover page for this Annual Report on Form 10-K for the year ended December 31, 2024 is contained in Exhibit 101 and has been formatted in Inline XBRLX

(*) The certification attached as Exhibit 32 that accompanies this Annual Report on Form 10-K is not deemed filed with the SEC and is not to be incorporated by reference into any filing of Wave Life Sciences Ltd. under the Securities Act of 1933, as amended, or the

Securities Exchange Act of 1934, as amended, whether made before or after the date of this Form 10-K, irrespective of any general incorporation language contained in such filing.

(+) Indicates management contract or compensatory plan or arrangement.

(†) Confidential treatment has been granted with respect to certain portions of this exhibit. Omitted portions have been filed separately with the SEC.

(††) Certain confidential portions of this Exhibit were omitted by means of marking such portions with brackets (“[***]”) because the identified confidential portions (i) are not material and (ii) is the type that the Registrant treats as private or confidential.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.