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GYRE THERAPEUTICS INC

For the period ended Dec 31, 2023. Filed Mar 27, 2024.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2023 · Filed Mar 27, 2024

GYRE$4.65-2.3%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

LIST OF EXHIBITS

Incorporated by reference
ExhibitNo.Exhibit titleFormFile No.ExhibitNo.Filing Date
2.1(a)†#Asset Purchase Agreement, dated as of December 26, 2022, by and among Catalyst Biosciences, Inc., GNI Group Ltd., and GNI Hong Kong Limited.8-K000-511732.1Dec. 27, 2022
2.1(b)Agreement and Amendment to Asset Purchase Agreement, dated as of March 29, 2023, by and among Catalyst Biosciences, Inc., GNI Group Ltd., and GNI Hong Kong Limited.8-K000-511732.2Mar. 30, 2023
2.2(a)#Business Combination Agreement, dated as of December 26, 2022, by and among Catalyst Biosciences, Inc., GNI USA, Inc., GNI Group Ltd., GNI Hong Kong Limited, Shanghai Genomics, Inc., the individuals listed on Annex A thereto and Continent Pharmaceuticals Inc.8-K000-511732.2Dec. 27, 2022
2.2(b)Amendment to Business Combination Agreement, dated as of March 29, 2023, by and among Catalyst Biosciences, Inc., GNI USA, Inc., GNI Group Ltd., GNI Hong Kong Limited, Shanghai Genomics, Inc., the Minority Holders and Continent Pharmaceuticals Inc.8-K000-511732.1Mar. 30, 2023
2.2(c)Second Amendment to Business Combination Agreement, dated as of August 30, 2023, by and among Catalyst Biosciences, Inc., GNI USA, Inc., GNI Group Ltd., GNI Hong Kong Limited, Shanghai Genomics, Inc. and Continent Pharmaceuticals Inc.8-K000-511732.1Aug. 31, 2023
3.1Fourth Amended and Restated Certificate of Incorporation of the Company.S-8333-1338814.1May 8, 2006
3.2Certificate of Amendment to Fourth the Amended and Restated Certificate of Incorporation of the Company.8-K000-511733.1Aug. 20, 2015
3.3Second Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of the Company.8-K000-511733.1Feb. 10, 2017
3.4Third Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of the Company.8-K000-511733.1Oct. 30, 2023
3.5Amended and Restated Bylaws of the Company.8-K000-511733.3Oct. 30, 2023
3.6(a)Certificate of Designation of Preferences, Rights and Limitations of Series A Convertible Preferred Stock, filed with the Delaware Secretary of State on April 10, 2017.8-K000-511733.1Apr. 13, 2017
Incorporated by reference
ExhibitNo.Exhibit titleFormFile No.ExhibitNo.Filing Date
3.6(b)* · Certificate of Elimination of Series A Preferred Stock, filed with the Delaware Secretary of State on March 25, 2024.
3.7(a)Certificate of Designation of Preferences, Rights and Limitations of Series X Convertible Preferred Stock, filed with the Delaware Secretary of State on December 27, 2022.8-K000-511733.1Dec. 27, 2022
3.7(b)Amendment to Certificate of Designation of Preferences, Rights and Limitations of Series X Convertible Preferred Stock, filed with the Delaware Secretary of State on October 30, 2023.8-K000-511733.2Oct. 30, 2023
3.8(a)Certificate of Designation of Preferences, Rights and Limitations of Series Y Preferred Stock, filed with the Delaware Secretary of State on June 20, 2023, with respect to the Series Y Preferred Stock.8-K000-511733.1June 20, 2023
3.8(b)Certificate of Elimination of Series Y Preferred Stock, filed with the Delaware Secretary of State on August 31, 2023.8-K000-511733.1Aug. 31, 2023
4.1Description of Securities.
4.2Warrant to Purchase Stock of Catalyst Biosciences, Inc., issued to Silicon Valley Bank on March 3, 2005.10-K000-511734.3Mar. 9, 2016
4.3Form of Warrant to Purchase Stock of Catalyst Biosciences, Inc., issued to purchasers of convertible promissory notes.10-K000-511734.5Mar. 9, 2016
4.4Form of Warrant to Purchase Series X Convertible Preferred Stock.8-K000-511734.1Oct. 30, 2023
10.1(a)#Contingent Value Rights Agreement, dated as of December 26, 2022, by and between Catalyst Biosciences, Inc. and American Stock Transfer & Trust Company, LLC.S-3333-2733952.5July 24, 2023
10.2(b)Amendment to Contingent Value Rights Agreement, dated as of March 29, 2023, by and between Catalyst Biosciences, Inc. and American Stock Transfer & Trust Company, LLC.8-K000-511732.3Mar. 30, 2023
10.3#Asset Purchase Agreement, dated as of February 27, 2023, by and between Catalyst Biosciences, Inc. and GC Biopharma Corp.8-K000-5117310.1Mar. 2, 2023
10.4Securities Purchase Agreement, dated as of October 27, 2023, by and between Catalyst Biosciences, Inc. and GNI USA, Inc.8-K000-5117310.1Oct. 30, 2023
10.5+Amended and Restated Employment Agreement, dated as of August 28, 2018, by and between Catalyst Biosciences, Inc. and Dr Nassim Usman.8-K000-5117310.1Aug. 31, 2018
Incorporated by reference
ExhibitNo.Exhibit titleFormFile No.ExhibitNo.Filing Date
10.6+Waiver Agreement between Catalyst Biosciences, Inc. and Dr. Nassim Usman, dated January 17, 2023.10-Q000-5117310.2May 15, 2023
10.7+Waiver Agreement between Catalyst Biosciences, Inc. and Dr. Grant Blouse, dated January 14, 2023.10-Q000-5117310.3May 15, 2023
10.8+Waiver Agreement between Catalyst Biosciences, Inc. and Ms. Seline Miller, dated January 17, 2023.10-Q000-5117310.4May 15, 2023
10.9+Catalyst Biosciences, Inc. (formerly Targacept, Inc.) 2015 Stock Incentive Plan (as Amended and Restated Effective June 9, 2016).DEF 14A000-51173Appendix AApr. 25, 2016
10.10+Form of Incentive Stock Option Award Notice.8-K000-5117310.1July 14, 2017
10.11+Form of Non-qualified Stock Option Award Notice.8-K000-5117310.2July 14, 2017
10.12+Catalyst Biosciences, Inc. 2018 Omnibus Incentive Plan.DEF 14A000-51173Appendix AMay 1, 2020
10.13+Catalyst Biosciences, Inc. 2018 Employee Stock Purchase Plan.DEF 14A000-51173Appendix BMay 11, 2018
10.14+Form of Stock Option Award Agreement.10-K000-5117310.8Mar. 31, 2022
10.15+Gyre Therapeutics, Inc. 2023 Omnibus Incentive Plan8-K000-5117310.2Oct. 30, 2023
10.16+Form of Indemnification Agreement8-K000-5117310.3Oct. 30, 2023
10.17+Employment Agreement, dated as of October 30, 2023, by and between the Company and Charles Wu.8-K000-5117310.4Oct. 30, 2023
10.18+Employment Agreement, dated as of October 30, 2023, by and between the Company and Ruoyu Chen.8-K000-5117310.5Oct. 30, 2023
10.19+Separation Agreement, dated October 30, 2023, by and between the Company and Dr. Nassim Usman.8-K000-5117310.1Nov. 2, 2023
10.20+Separation Agreement, dated October 30, 2023, by and between the Company and Seline Miller.8-K000-5117310.2Nov. 2, 2023
10.21+Employment Agreement, dated as of January 15, 2024, by and between the Company and Dr. Han Ying.8-K000-5117310.1Jan. 19, 2024
16.1Letter to the SEC from EisnerAmper LLC, dated November 2, 2023.8-K000-5117316.1Nov. 2, 2023
21.1*List of subsidiaries of the Company.
23.1*Consent of Grant Thornton Zhitong Certified Public Accountants LLP, Independent Registered Public Accounting Firm.
24.1*Power of Attorney (included as part of the signature page hereto).
Incorporated by reference
ExhibitNo.Exhibit titleFormFile No.ExhibitNo.Filing Date
31.1*Certification of the Chief Executive Officer pursuant to Rule 13a-14(a) and 15d-14(a) of the Securities Exchange Act of 1934, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
31.2*Certification of the Chief Financial Officer pursuant to Rule 13a-14(a) and 15d-14(a) of the Securities Exchange Act of 1934, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
32.1**Certification of the Chief Executive Officer pursuant to Rule 13a-14(b) of the Exchange Act and 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
32.2**Certification of the Chief Financial Officer pursuant to Rule 13a-14(b) of the Exchange Act and 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
97.1*Clawback Policy of the Company
101.INS*Inline XBRL Instance Document
101.SCH*Inline XBRL Taxonomy Extension Schema Document
101.CAL*Inline XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF*Inline XBRL Taxonomy Extension Definition Linkbase Document
101.LAB*Inline XBRL Taxonomy Extension Label Linkbase Document
101.PRE*Inline XBRL Taxonomy Extension Presentation Linkbase Document
104Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)
  • Filed herewith.

** Furnished.

† The annexes, schedules, and certain exhibits to this Exhibit have been omitted pursuant to Item 601(a)(5).

Pursuant to Item 601(b)(10) of Regulation S-K, certain confidential portions of this exhibit were omitted by means of marking such portions with an asterisk because the identified confidential portions (i) the Company customarily and actually treats that information as private or confidential and (ii) the information was not material.

  • Denotes management contract, compensatory plan or arrangement.
ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.