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VERTEX PHARMACEUTICALS INC / MA

For the period ended Dec 31, 2025. Filed Feb 13, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 13, 2026

VRTX$550.87+0.7%Stored close · as of Nov 9, 2026

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Item 9B. Other Information

Rule 10b5-1 Trading Plans

Our policy governing transactions in our securities by our directors, officers, and employees permits our officers,

directors and employees to enter into trading plans complying with Rule 10b5-1 under the Exchange Act. The following table

describes the written plans for the sale of our securities adopted by our directors and officers (as defined in Rule 16a-1(f)

under the Exchange Act) during the fourth quarter of 2025, each of which is intended to satisfy the affirmative defense

conditions of Rule 10b5-1 (each, a “Trading Plan”). Other than as described in the table below, none of our directors or

officers adopted, modified orterminated a Trading Plan in the fourth quarter of 2025.

Name and TitleDate of Adoption of Trading PlanScheduled Expiration Date of Trading Plan(1)Maximum Shares Subject to Trading Plan
Reshma KewalramaniChief Executive Officer and President11/17/202511/16/202640,000
Amit SachdevEVP, Chief Patient and External Affairs Officer11/18/202510/30/202670,498(2)
Carmen BozicEVP, Global Medicines Development and Medical Affairs, Chief Medical Officer11/20/202511/02/202634,733(2)
Duncan McKechnieEVP, Chief Commercial Officer11/25/202511/13/202617,367(2)
(1) A Trading Plan may expire on an earlier date if all contemplated transactions are completed before such Trading Plan’s expiration date, upon termination by broker or the holder of the Trading Plan, or as otherwise provided in the Trading Plan.
(2) The maximum shares listed has not been reduced by the number of shares of common stock that will be withheld to satisfy tax withholding obligations at future vesting dates because such number of shares is not yet determinable.

2026 Restated Articles of Organization

On February 12, 2026, the Company filed Restated Articles of Organization with the Secretary of the Commonwealth of

Massachusetts to consolidate its Articles of Organization and all prior amendments and to remove references to the Series A

Junior Participating Preferred Stock, which is no longer outstanding. The restatement was effected for clarity only and did not

result in any changes to the rights of holders of the Company’s common stock.

A copy of the Restated Articles of Organization is filed as Exhibit 3.1 to this Annual Report on Form 10-K and is

incorporated herein by reference.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.