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IONIS PHARMACEUTICALS INC

For the period ended Sep 30, 2026. Filed Nov 9, 2026.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2026 · Filed Nov 9, 2026

IONS$31.00-21.4%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

See the whole filing, with its images and exhibits

Index

PART I · FINANCIAL INFORMATION
ITEM 1: · Financial Statements:
Condensed Consolidated Balance Sheets as of September 30, 2026 (unaudited) and December 31, 20253
Condensed Consolidated Statements of Operations for the three and nine months ended September 30, 2026 and 2025 (unaudited)4
Condensed Consolidated Statements of Comprehensive Loss for the three and nine months ended September 30, 2026 and 2025 (unaudited)5
Condensed Consolidated Statements of Stockholders’ Equity for the three and nine months ended September 30, 2026 and 2025 (unaudited)6
Condensed Consolidated Statements of Cash Flows for the nine months ended September 30, 2026 and 2025 (unaudited)8
Notes to Condensed Consolidated Financial Statements (unaudited)9
ITEM 2:Management’s Discussion and Analysis of Financial Condition and Results of Operations:
Overview28
Critical Accounting Estimates30
Results of Operations31
Liquidity and Capital Resources37
ITEM 3:Quantitative and Qualitative Disclosures about Market Risk39
ITEM 4:Controls and Procedures39
PART IIOTHER INFORMATION40
ITEM 1:Legal Proceedings40
ITEM 1A:Risk Factors40
ITEM 2:Unregistered Sales of Equity Securities and Use of Proceeds58
ITEM 3:Default upon Senior Securities58
ITEM 4:Mine Safety Disclosures58
ITEM 5:Other Information58
ITEM 6:Exhibits59
SIGNATURES60

TRADEMARKS

“Ionis,” the Ionis logo, and other trademarks or service marks of Ionis Pharmaceuticals, Inc. appearing in this report are the property of Ionis Pharmaceuticals, Inc. “Akcea,” the Akcea logo, and other trademarks or service marks of Akcea Therapeutics, Inc. appearing in this report are the property of Akcea Therapeutics, Inc., Ionis’ wholly owned subsidiary. This report contains additional trade names, trademarks and service marks of others, which are the property of their respective owners. Solely for convenience, trademarks and trade names referred to in this report may appear without the ® or TM symbols.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.