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IONIS PHARMACEUTICALS INC

For the period ended Jun 30, 2026. Filed Jul 29, 2026.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2026 · Filed Jul 29, 2026

IONS$28.19-9.1%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Condensed Consolidated Statements of Cash Flows

Six Months Ended
June 30,
2026 · 2025
Operating activities:
Net loss$(207,174)$(23,387)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation6,7344,494
Amortization of right-of-use operating lease assets6,9905,177
Amortization of other assets1,3611,180
Amortization of discount on investments, net(9,533)(12,978)
Amortization of debt issuance costs4,1503,288
Non-cash royalty revenue related to sale of royalties(22,387)(24,894)
Non-cash interest related to sale of future royalties34,53837,165
Stock-based compensation expense88,87059,408
Loss (gain) on investments, net(12,401)20,471
Non-cash losses related to other assets481297
Changes in operating assets and liabilities:
Contracts receivable7,21439,608
Inventories(24,626)(12,465)
Other current and long-term assets(38,265)(22,536)
Accounts payable18,583(20,309)
Income taxes16447
Accrued compensation(65,943)(23,050)
Accrued liabilities and other liabilities12,8513,535
Deferred contract revenue(28,895)(34,488)
Net cash provided by (used in) operating activities(227,288)563
Investing activities:
Purchases of short-term investments(513,005)(802,657)
Proceeds from sale of short-term investments1,114,805880,545
Purchases of property, plant and equipment(37,843)(24,882)
Acquisition of licenses and other assets, net(3,640)(2,615)
Net cash provided by investing activities560,31750,391
Financing activities:
Proceeds from issuance of common stock through equity plans, net77,5603,528
Repayment of 0 percent convertible senior notes due 2026(432,511)-
Principal payments on mortgage debt(85)(82)
Net cash provided by (used in) financing activities(355,036)3,446
Effects of exchange rates on cash(188)827
Net increase (decrease) in cash and cash equivalents(22,195)55,227
Cash and cash equivalents at beginning of period372,260242,077
Cash and cash equivalents at end of period$350,065$297,304
Supplemental disclosures of cash flow information:
Interest paid$5,212$5,214
Income taxes paid (refunds received), net$1,200$(383)
Supplemental disclosures of non-cash investing and financing activities:
Right-of-use assets obtained in exchange for lease obligations$-$7,253
Amounts accrued for capital and patent expenditures$1,042$145
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.