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IONIS PHARMACEUTICALS INC

For the period ended Mar 31, 2026. Filed Apr 29, 2026.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Mar 31, 2026 · Filed Apr 29, 2026

IONS$39.42+1.6%Stored close · as of Nov 6, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

See the whole filing, with its images and exhibits

Table of Contents

PART I · FINANCIAL INFORMATION
ITEM 1: · Financial Statements:
Condensed Consolidated Balance Sheets as of March 31, 2026 (unaudited) and December 31, 20253
Condensed Consolidated Statements of Operations for the three months ended March 31, 2026 and 2025 (unaudited)4
Condensed Consolidated Statements of Comprehensive Loss for the three months ended March 31, 2026 and 2025 (unaudited)5
Condensed Consolidated Statements of Stockholders’ Equity for the three months ended March 31, 2026 and 2025 (unaudited)6
Condensed Consolidated Statements of Cash Flows for the three months ended March 31, 2026 and 2025 (unaudited)7
Notes to Condensed Consolidated Financial Statements (unaudited)8
ITEM 2:Management’s Discussion and Analysis of Financial Condition and Results of Operations:
Overview24
Critical Accounting Estimates27
Results of Operations27
Liquidity and Capital Resources33
ITEM 3:Quantitative and Qualitative Disclosures about Market Risk35
ITEM 4:Controls and Procedures35
PART IIOTHER INFORMATION34
ITEM 1:Legal Proceedings36
ITEM 1A:Risk Factors36
ITEM 2:Unregistered Sales of Equity Securities and Use of Proceeds54
ITEM 3:Default upon Senior Securities54
ITEM 4:Mine Safety Disclosures54
ITEM 5:Other Information55
ITEM 6:Exhibits56
SIGNATURES57

TRADEMARKS

“Ionis,” the Ionis logo, and other trademarks or service marks of Ionis Pharmaceuticals, Inc. appearing in this report are the property of Ionis Pharmaceuticals, Inc. “Akcea,” the Akcea logo, and other trademarks or service marks of Akcea Therapeutics, Inc. appearing in this report are the property of Akcea Therapeutics, Inc., Ionis’ wholly owned subsidiary. This report contains additional trade names, trademarks and service marks of others, which are the property of their respective owners. Solely for convenience, trademarks and trade names referred to in this report may appear without the ® or TM symbols.

PART I — FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.