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IONIS PHARMACEUTICALS INC

For the period ended Sep 30, 2025. Filed Oct 29, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2025 · Filed Oct 29, 2025

IONS$31.00-21.4%Stored close · as of Nov 9, 2026

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Item 5. Other Information

ITEM 5.

OTHER INFORMATION

Trading Plans

During the quarter ended September 30, 2025, our directors and officers (as defined in Rule 16a-1(f) under the Exchange Act), or Section 16 officers and directors, adopted or terminated contracts, instructions or written plans for the purchase or sale of our securities as noted in the table below.

  • Contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act.

** "Non-Rule 10b5-1 trading arrangement" as defined in item 408(c) of Regulation S-K under the Exchange Act.

Trading Arrangement · Total Shares
Name · Title · Action · Date · Rule 10b5-1* · Non-Rule 10b5-1** · to be Sold · Expiration Date
Spencer BerthelsenBoard MemberAdoptionSeptember 12, 2025X16,000The earlier to occur of (i) July 1, 2026, and (ii) Upon the execution of all instructions provided in the plan

Index

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.