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IONIS PHARMACEUTICALS INC

For the period ended Sep 30, 2025. Filed Oct 29, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2025 · Filed Oct 29, 2025

IONS$39.42+1.6%Stored close · as of Nov 6, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

See the whole filing, with its images and exhibits

Index

PART I · FINANCIAL INFORMATION
ITEM 1: · Financial Statements:
Condensed Consolidated Balance Sheets as of September 30, 2025 (unaudited) and December 31, 20243
Condensed Consolidated Statements of Operations for the three and nine months ended September 30, 2025 and 2024 (unaudited)4
Condensed Consolidated Statements of Comprehensive Loss for the three and nine months ended September 30, 2025 and 2024 (unaudited)5
Condensed Consolidated Statements of Stockholders’ Equity for the three and nine months ended September 30, 2025 and 2024 (unaudited)6
Condensed Consolidated Statements of Cash Flows for the nine months ended September 30, 2025 and 2024 (unaudited)8
Notes to Condensed Consolidated Financial Statements (unaudited)9
ITEM 2:Management’s Discussion and Analysis of Financial Condition and Results of Operations:
Overview23
Critical Accounting Estimates25
Results of Operations26
Liquidity and Capital Resources31
ITEM 3:Quantitative and Qualitative Disclosures about Market Risk33
ITEM 4:Controls and Procedures33
PART IIOTHER INFORMATION34
ITEM 1:Legal Proceedings34
ITEM 1A:Risk Factors34
ITEM 2:Unregistered Sales of Equity Securities and Use of Proceeds52
ITEM 3:Default upon Senior Securities52
ITEM 4:Mine Safety Disclosures52
ITEM 5:Other Information52
ITEM 6:Exhibits53
SIGNATURES54

TRADEMARKS

“Ionis,” the Ionis logo, and other trademarks or service marks of Ionis Pharmaceuticals, Inc. appearing in this report are the property of Ionis Pharmaceuticals, Inc. “Akcea,” the Akcea logo, and other trademarks or service marks of Akcea Therapeutics, Inc. appearing in this report are the property of Akcea Therapeutics, Inc., Ionis’ wholly owned subsidiary. This report contains additional trade names, trademarks and service marks of others, which are the property of their respective owners. Solely for convenience, trademarks and trade names referred to in this report may appear without the ® or TM symbols.

Index

PART I — FINANCIAL INFORMATION

ITEM 1.

FINANCIAL STATEMENTS

ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.