IONIS PHARMACEUTICALS INC
For the period ended Sep 30, 2025. Filed Oct 29, 2025.
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A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.
Sep 30, 2025 · Filed Oct 29, 2025
IONS$28.19-9.1%Stored close · as of Nov 10, 2026
Extracted filing text, with the paragraph anchors used by the comparison.
See the whole filing, with its images and exhibitsContents
Condensed Consolidated Statements of Operations
(in thousands, except per share amounts)
| Three Months Ended · Nine Months Ended | ||||||
|---|---|---|---|---|---|---|
| September 30, · September 30, | ||||||
| 2025 · 2024 · 2025 · 2024 | ||||||
| Revenue: | ||||||
| Commercial revenue: | ||||||
| Product sales, net | $31,792 | $ | - | $57,353 | $ | - |
| Royalty revenue | 75,694 | 66,807 | 209,811 | 180,036 | ||
| Other commercial revenue | 8,112 | 8,924 | 27,359 | 27,324 | ||
| Total commercial revenue | 115,598 | 75,731 | 294,523 | 207,360 | ||
| Research and development revenue: | ||||||
| Collaborative agreement revenue | 31,436 | 44,883 | 413,387 | 235,753 | ||
| WAINUA joint development revenue | 9,685 | 13,200 | 32,471 | 35,449 | ||
| Total research and development revenue | 41,121 | 58,083 | 445,858 | 271,202 | ||
| Total revenue | 156,719 | 133,814 | 740,381 | 478,562 | ||
| Expenses: | ||||||
| Cost of sales | 2,338 | 1,071 | 7,952 | 7,385 | ||
| Research, development and patent | 217,754 | 219,761 | 635,973 | 656,040 | ||
| Selling, general and administrative | 96,809 | 61,638 | 263,681 | 179,395 | ||
| Total operating expenses | 316,901 | 282,470 | 907,606 | 842,820 | ||
| Loss from operations | (160,182) | (148,656) | (167,225) | (364,258) | ||
| Other income (expense): | ||||||
| Investment income | 23,682 | 26,228 | 73,035 | 78,112 | ||
| Interest expense | (4,212) | (4,161) | (12,434) | (12,803) | ||
| Interest expense related to sale of future royalties | (17,952) | (18,533) | (55,422) | (54,788) | ||
| Gain (loss) on investments, net | 29,908 | 879 | 9,432 | (321) | ||
| Other income, net | 363 | 142 | 929 | 1,029 | ||
| Loss before income tax benefit (expense) | (128,393) | (144,101) | (151,685) | (353,029) | ||
| Income tax benefit (expense) | (213) | 3,621 | (308) | 3,481 | ||
| Net loss | $(128,606) | $(140,480) | $(151,993) | $(349,548) | ||
| Basic and diluted net loss per share | (0.80) | $(0.95) | $(0.95) | $(2.38) | ||
| Shares used in computing basic and diluted net loss per share | 159,765 | 148,593 | 159,216 | 146,703 | ||
Index
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