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IONIS PHARMACEUTICALS INC

For the period ended Jun 30, 2025. Filed Jul 30, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2025 · Filed Jul 30, 2025

IONS$28.19-9.1%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Condensed Consolidated Statements of Cash Flows

Six Months Ended
June 30,
2025 · 2024
Operating activities:
Net loss$(23,387)$(209,068)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Depreciation4,4945,013
Amortization of right-of-use operating lease assets5,1774,957
Amortization of other assets1,1801,260
Amortization of discount on investments, net(12,978)(19,143)
Amortization of debt issuance costs3,2883,338
Non-cash royalty revenue related to sale of royalties(24,894)(16,236)
Non-cash interest related to sale of future royalties37,16535,949
Stock-based compensation expense59,40862,068
Loss on investments, net20,4711,201
Non-cash losses related to other assets297389
Changes in operating assets and liabilities:
Contracts receivable39,60870,519
Inventories(12,465)(298)
Other current and long-term assets(22,536)(9,381)
Accounts payable(20,309)(17,064)
Income taxes47(1,867)
Accrued compensation(23,050)(32,709)
Accrued liabilities and other current liabilities3,535(39,201)
Deferred contract revenue(34,488)(109,545)
Net cash provided by (used in) operating activities563(269,818)
Investing activities:
Purchases of short-term investments(802,657)(803,867)
Proceeds from sale of short-term investments880,545968,413
Purchases of property, plant and equipment(24,882)(10,727)
Acquisition of licenses and other assets, net(2,615)(15,264)
Net cash provided by investing activities50,391138,555
Financing activities:
Proceeds from issuance of common stock through equity plans, net3,52826,205
Principal payments on mortgage debt(82)(78)
Net cash provided by financing activities3,44626,127
Effects of exchange rates on cash827(137)
Net increase (decrease) in cash and cash equivalents55,227(105,273)
Cash and cash equivalents at beginning of period242,077399,266
Cash and cash equivalents at end of period$297,304$293,993
Supplemental disclosures of cash flow information:
Interest paid$5,214$5,569
Income taxes paid (refunds received), net$(383)$1,992
Supplemental disclosures of non-cash investing and financing activities:
Right-of-use assets obtained in exchange for lease obligations$7,253$-
Amounts accrued for capital and patent expenditures$145$1,453

Index

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.