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IONIS PHARMACEUTICALS INC

For the period ended Dec 31, 2024. Filed Feb 19, 2025.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2024 · Filed Feb 19, 2025

IONS$31.00-21.4%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Consolidated Statements of Operations

(In thousands, except for per share amounts)

Year Ended December 31,
202420232022
Revenue:
Commercial revenue:
SPINRAZA royalties$216,090$240,379$242,314
WAINUA royalties20,207——
Other commercial revenue56,77968,21261,044
Total commercial revenue293,076308,591303,358
Research and development revenue:
Collaborative agreement revenue332,647352,657207,222
WAINUA joint development revenue79,415126,39976,787
Total research and development revenue412,062479,056284,009
Total revenue705,138787,647587,367
Expenses:
Cost of sales11,2159,13314,116
Research, development and patent901,530899,625833,147
Selling, general and administrative267,474232,619150,295
Total operating expenses1,180,2191,141,377997,558
Loss from operations(475,081)(353,730)(410,191)
Other income (expense):
Investment income107,02289,04125,331
Interest expense(16,994)(12,660)(8,122)
Interest expense related to sale of future royalties(73,457)(68,797)—
Loss on investments(2,889)(1,914)(7,333)
Gain (loss) on sale of real estate assets(12)(161)149,604
Other income (expense)1,34314,256(7,274)
Loss before income tax benefit (expense)(460,068)(333,965)(257,985)
Income tax benefit (expense)6,171(32,321)(11,737)
Net loss$(453,897)$(366,286)$(269,722)
Basic and diluted net loss per share$(3.04)$(2.56)$(1.90)
Shares used in computing basic and diluted net loss per share149,514143,190141,848
ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.