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IONIS PHARMACEUTICALS INC

For the period ended Dec 31, 2023. Filed Feb 21, 2024.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2023 · Filed Feb 21, 2024

IONS$28.19-9.1%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 8. Consolidated Statements of Cash Flows

CONSOLIDATED STATEMENTS OF CASH FLOWS

Year Ended December 31,
202320222021
Operating activities:
Net loss$(366,286)$(269,722)$(28,597)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Depreciation10,29214,32815,487
Amortization of right-of-use operating lease assets9,6475,3621,721
Amortization of other assets2,5592,4152,352
Amortization of premium (discount) on investments, net(28,885)7,38917,776
Amortization of debt issuance costs6,3305,3734,958
Non-cash royalty revenue related to sale of royalties(44,628)——
Non-cash interest related to sale of future royalties68,238——
Stock-based compensation expense105,809100,264120,678
Loss (gain) on early retirement of debt(13,389)—8,627
Non-cash losses related to disposal of property, plant and equipment16,649531—
Loss (gain) on sale of real estate assets161(150,135)—
Loss (gain) on investments1,589224(1,092)
Non-cash losses related to other assets1,6612,0302,707
Changes in operating assets and liabilities:
Contracts receivable(72,059)36,35814,308
Inventories(6,392)2,773(2,841)
Other current and long-term assets(29,840)(24,682)(877)
Accounts payable8,1191,094(6,000)
Income taxes(4,098)6,213(280)
Accrued compensation18,54910,368(26,918)
Accrued liabilities and other current liabilities(5,506)46,695(8,381)
Deferred contract revenue13,967(71,248)(82,829)
Net cash provided by (used in) operating activities(307,513)(274,370)30,799
Investing activities:
Purchases of short-term investments(1,770,814)(1,485,772)(1,124,193)
Proceeds from sale of short-term investments1,584,676989,1521,344,185
Purchases of property, plant and equipment(23,805)(15,721)(11,955)
Proceeds from sale of real estate assets22254,083—
Acquisition of licenses and other assets, net(4,206)(4,378)(5,946)
Purchases of strategic investments——(7,185)
Net cash provided by (used in) investing activities(214,127)(262,636)194,906
Financing activities:
Proceeds from equity, net49,4426,37311,565
Payments of tax withholdings related to vesting of employee stock awards and exercise of employee stock options—(10,953)(16,725)
Proceeds from issuance of 1.75 percent convertible senior notes575,000——
1.75 percent convertible senior notes issuance costs(14,175)——
Repurchase of $504.4 million principal amount of 0.125 percent convertible senior notes(487,943)——
Proceeds from sale of future royalties500,000——
Payments of transaction costs related to sale of future royalties(10,434)(29)—
Proceeds from real estate transaction32,352——
Proceeds from the issuance of 0 percent convertible senior notes——632,500
0 percent convertible senior notes issuance costs——(15,609)
Repurchase of $247.9 million principal amount of 1 percent convertible senior notes——(256,963)
Repayment of remaining principal amount of 1 percent convertible senior notes at maturity——(61,967)
Proceeds from issuance of warrants——89,752
Purchase of note hedges——(136,620)
Principal payments on debt(160)(50,686)—
Net cash provided by (used in) financing activities644,082(55,295)245,933
Effects of exchange rates on cash352(418)(111)
Net increase (decrease) in cash and cash equivalents122,794(592,719)471,527
Cash and cash equivalents at beginning of year276,472869,191397,664
Cash and cash equivalents at end of year$399,266$276,472$869,191
Supplemental disclosures of cash flow information:
Interest paid$6,512$2,898$4,778
Income taxes paid$48,334$5,010$38
Supplemental disclosures of non-cash investing and financing activities:
Right-of-use assets obtained in exchange for lease liabilities$—$168,931$6,641
Amounts accrued for capital and patent expenditures$172$4,767$705
ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.