FIFTH THIRD BANCORP

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Management’s Discussion and Analysis of Financial Condition and Results of Operations (continued)

BALANCE SHEET ANALYSIS

Loans and Leases

The Bancorp classifies its commercial loans and leases based upon primary purpose and consumer loans based upon product or collateral. The following table presents the end of period components of loans and leases, including loans and leases held for sale:

Total loans and leases, including loans and leases held for sale, increased $57.6 billion, or 47%, from December 31, 2025 primarily driven by the Comerica acquisition as the Bancorp acquired commercial and consumer loans and leases of $50.5 billion at acquisition. Table 15 summarizes the detail of loans and leases acquired as a result of the Comerica acquisition on February 1, 2026.

The following discussion excludes the initial impact of the loans and leases acquired in the Comerica acquisition on February 1, 2026. Commercial loans and leases increased $6.5 billion, or 9%, from December 31, 2025 primarily due to increases in commercial and industrial loans and commercial construction loans. Commercial and industrial loans increased $4.9 billion, or 9%, from December 31, 2025 primarily as a result of loan originations exceeding payoffs as well as increased line utilization. Commercial construction loans increased $1.1 billion, or 20%, from December 31, 2025 as loan originations exceeded payoffs.

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Investment Securities

The Bancorp uses investment securities as a means of managing interest rate risk, providing collateral for pledging purposes and for liquidity risk management. The carrying value of total investment securities, which consist of available-for-sale debt and other securities, held-to-maturity securities, trading debt securities and equity securities, was $66.1 billion and $49.0 billion at September 30, 2026 and December 31, 2025, respectively. The increase in total investment securities reflects the impact of the Comerica acquisition, including $7.2 billion of available-for-sale debt and other securities, $3.7 billion of held-to-maturity securities, $170 million of trading debt securities and $141 million of equity securities acquired on February 1, 2026.

Debt securities are classified as available-for-sale when, in management’s judgment, they may be sold in response to, or in anticipation of, changes in market conditions. Debt securities that management has the intent and ability to hold to maturity are classified as held-to-maturity and reported at amortized cost. Debt securities are classified as trading typically when bought and held principally for the purpose of selling them in the near term. The taxable available-for-sale debt and other securities portfolio had an effective duration of 4.2 and 3.8 at September 30, 2026 and December 31, 2025, respectively. The taxable held-to-maturity securities portfolio had an effective duration of 4.9 and 5.1 at September 30, 2026 and December 31, 2025, respectively.

At September 30, 2026, the Bancorp’s investment securities portfolio consisted primarily of U.S. Treasury and other government guaranteed securities. The Bancorp held an immaterial amount of below-investment grade available-for-sale debt securities and held-to-maturity securities at both September 30, 2026 and December 31, 2025. At both September 30, 2026 and December 31, 2025, the Bancorp did not recognize an allowance for credit losses for its investment securities. The Bancorp also did not recognize provision for credit losses for investment securities during both the three and nine months ended September 30, 2026 and 2025.

The Bancorp recognized impairment losses of zero and $7 million on its available-for-sale debt and other securities for the three and nine months ended September 30, 2026, respectively. The Bancorp recognized an immaterial amount of impairment losses on its available-for-sale debt and other securities for both the three and nine months ended September 30, 2025. These losses were included in securities gains (losses), net, in the Condensed Consolidated Statements of Income and related to certain securities in unrealized loss positions where the Bancorp had determined that it no longer intended to hold the securities until the recovery of their amortized cost bases.

The following table summarizes the end of period components of investment securities:

(a)Other securities consist of FHLB, FRB and DTCC restricted stock hold ings that are carried at cost.

(b)Includes a discount of $653 and $742 at September 30, 2026 and December 31, 2025, respectively, pertaining to the remaining unamortized portion of unrealized losses on securities transferred to HTM.

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The following table presents the estimated future amortization of unrealized losses related to investment securities transferred from available-for-sale to held-to-maturity. At September 30, 2026, these transferred securities had an estimated weighted-average life of 6.4 years.

On an amortized cost basis, available-for-sale debt and other securities and held-to-maturity securities comprised 26% of total interest-earning assets at both September 30, 2026 and December 31, 2025. The estimated weighted-average life of the debt securities in the available-for-sale debt and other securities portfolio was 5.5 years and 5.1 years at September 30, 2026 and December 31, 2025, respectively. In addition, the debt securities in the available-for-sale debt and other securities portfolio had a weighted-average yield of 3.52% and 3.09% at September 30, 2026 and December 31, 2025, respectively. The held-to-maturity securities portfolio had an estimated weighted-average life of 5.9 years and 6.4 years at September 30, 2026 and December 31, 2025, respectively. In addition, the held-to-maturity securities portfolio had a weighted-average yield of 4.07% and 3.50% at September 30, 2026 and December 31, 2025, respectively.

Information presented in Tables 18 and 19 is on a weighted-average life basis, anticipating future prepayments. Yield information is presented on an FTE basis and is computed using amortized cost balances and reflects the impact of prepayments. Maturity and yield calculations for the total available-for-sale debt and other securities portfolio exclude other securities that have no stated yield or maturity.

The fair values of investment securities are impacted by interest rates, credit spreads, market volatility and liquidity conditions. The fair value of the Bancorp’s investment securities portfolio generally decreases when interest rates increase or when credit spreads widen, and, conversely, increases when interest rates decrease or when credit spreads contract. Total net unrealized losses on the available-for-sale debt and other securities portfolio were $4.7 billion and $2.9 billion at September 30, 2026 and December 31, 2025, respectively.

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(a)Taxable-equivalent yield adjustments included in the above table are 0.06% and 0.02% for securities with an average life between 5 and 10 years and in total, respectively.

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(a)Taxable-equivalent yield adjustments included in the above table are 0.01%, 0.07%, 1.11% and 0.08% for securities with an average life between one and five years, average life between 5 and 10 years, average life greater than 10 years and in total, respectively.

(b)Includes a discount of $653 pertaining to the unamortized portion of unrealized losses on securities transferred to HTM.

Other Short-Term Investments

Other short-term investments have original maturities of less than one year and primarily include interest-bearing balances that are funds on deposit at the FRB or other depository institutions. Other short-term investments are used as an extension of the investment securities portfolio to manage liquidity risk. Other short-term investments were $16.5 billion at September 30, 2026, a decrease of $2.4 billion from December 31, 2025. The decrease was primarily driven by the strategic redeployment of liquidity into investment securities to proactively manage interest rate risk, wholesale funding maturities that were not replaced, as well as growth in loans and leases during the nine months ended September 30, 2026, partially offset by an increase in core deposits, including the migration of former off-balance-sheet Comerica investment sweep balances onto the balance sheet during the third quarter of 2026, and other short-term investment balances acquired in connection with the acquisition of Comerica.

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Deposits

The Bancorp’s deposit balances represent an important source of funding and revenue growth opportunity. The Bancorp continues to focus on core deposit growth in its retail and commercial franchises by improving customer satisfaction, building full relationships and offering competitive rates and through its strategy of expanding retail presence in high-growth markets, such as in the Southeast and Texas.

The following table presents the end of period components of deposits:

(a)Includes $1 and $777 of retail brokered CDs which are fully covered by FDIC insurance as of September 30, 2026 and December 31, 2025, respectively.

Total deposits increased $67.7 billion, or 39%, from December 31, 2025 primarily due to the Comerica acquisition as the Bancorp assumed commercial and consumer deposit balances of $65.2 billion at acquisition. Table 21 summarizes the detail of deposits assumed as a result of the Comerica acquisition on February 1, 2026.

The following discussion excludes the initial impact of the deposits assumed in the Comerica acquisition on February 1, 2026. Core deposits increased $4.0 billion, or 2%, from December 31, 2025 primarily due to an increase in transaction deposits, partially offset by a decrease in CDs $250,000 or less. Transaction deposits increased $5.0 billion, or 3%, from December 31, 2025 primarily driven by an increase in interest checking deposits, partially offset by a decrease in money market deposits. Interest checking deposits increased $7.0 billion, or 11%, from December 31, 2025 primarily due to the migration of former off-balance-sheet Comerica investment sweep balances onto the balance sheet during the third quarter of 2026 as well as certain Comerica legacy deposit products that were simplified into more modern interest checking products resulting in a shift from money market deposits into commercial interest checking deposits during the third quarter of 2026. Additionally, the increase in interest checking deposits is partially attributable to higher balances per commercial customer account. Money market deposits decreased $1.4 billion, or 4%, from December 31, 2025 primarily as a result of the aforementioned shift of certain Comerica legacy deposit products from commercial money market deposits to commercial interest checking deposits occurring in the third quarter of 2026, partially offset by higher offering rates from promotional offers and branch expansion leading to growth in the number of consumer customer accounts as well as higher balances per consumer customer account. CDs $250,000 or less decreased $1.1 billion, or 10%, from December 31, 2025 primarily due to lower balances per customer account driven by maturities which outpaced new issuances given current market conditions.

CDs over $250,000 decreased $1.5 billion, or 75%, from December 31, 2025 primarily due to maturities of retail brokered CDs.

Deposit insurance

The FDIC generally provides a standard amount of insurance of $250,000 per depositor, per insured bank, for each account ownership category defined by the FDIC. As of September 30, 2026 and December 31, 2025, approximately $137.6 billion, or 58%, and $101.8 billion, or 59%, respectively, of the Bancorp’s domestic deposits were estimated to be insured. As of September 30, 2026 and December 31, 2025, approximately $101.5 billion and $69.8 billion, respectively, of the Bancorp’s domestic deposits were estimated to be uninsured. At September 30, 2026 and December 31, 2025, approximately $1.9 billion and $1.1 billion, respectively, of domestic time deposits were

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estimated to be uninsured. Where information is not readily available to determine the amount of insured deposits, the amount of uninsured deposits is estimated, consistent with the methodologies and assumptions utilized in providing information to the Bank’s regulators.

Borrowings

The Bancorp accesses a variety of short-term and long-term funding sources. Borrowings with original maturities of one year or less are classified as short-term and include federal funds purchased and other short-term borrowings. For further information on the components of short-term borrowings, refer to Note 13 of the Notes to Condensed Consolidated Financial Statements.

The following table summarizes the end of period components of borrowings:

Total borrowings increased $3.6 billion, or 25%, from December 31, 2025 primarily due to an increase in long-term debt of $3.3 billion driven by long-term debt assumed in the Comerica acquisition totaling $5.5 billion. Additionally, the increase from December 31, 2025 included the issuance of senior fixed-rate/floating-rate notes in January 2026 totaling $2.0 billion, which was more than offset by $3.7 billion of redemptions and maturities and $285 million of fair value adjustments associated with hedged long-term debt. For further information regarding long-term debt activity, refer to Note 14 of the Notes to Condensed Consolidated Financial Statements.